SCHEMBL98089

SCHEMBL98089

COc1cc(N)ccc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 5/20 0.55
KDM4E B2RXH2 4/20 0.55
GAA P10253 3/20 0.55
CYP3A4 P08684 2/20 0.55
ESR2 Q92731 1/20 0.55
PTPN1 P18031 1/20 0.55
HPGD P15428 3/20 0.53
TDP1 Q9NUW8 3/20 0.50
MEN1 O00255 2/20 0.50
THRB P10828 2/20 0.50
RECQL P46063 2/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
USP2 O75604 1/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
APEX1 P27695 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8000660 0.86 ALDH1A1 (0.76) ALDH1A1MAPTKDM4EGAACYP3A4
SCHEMBL8718150 0.85 ALDH1A1 (0.72) ALDH1A1MAPTKDM4EGAACYP3A4
SCHEMBL98371 0.85 ALDH1A1 (0.73) ALDH1A1MAPTKDM4EGAACYP3A4
SCHEMBL8280033 0.85 ALDH1A1 (0.73) ALDH1A1MAPTKDM4EGAACYP3A4
SCHEMBL1354320 0.85 ALDH1A1 (0.73) ALDH1A1MAPTKDM4EGAAHPGD
SCHEMBL6760942 0.84 ALDH1A1 (0.70) ALDH1A1MAPTKDM4EGAAHPGD
SCHEMBL224165 0.83 ALDH1A1 (0.71) ALDH1A1MAPTKDM4EGAAHPGD
Aminosalicylic Acid SCHEMBL6760940 0.83 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EGAACYP3A4
SCHEMBL1443873 0.82 ALDH1A1 (0.70) ALDH1A1MAPTKDM4EGAACYP3A4
Hydrochloric Acid SCHEMBL7410231 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 783 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12264219-B2 Conductive benzoic acid based polymer containing biomaterial for enhancement of tissue conduction in vitro and in vivo UNIVERSITY HEALTH NETWORK (CA) 2025-04-01 US claimed
EP-3658625-B1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIV HEALTH NETWORK (CA) 2024-06-12 EP claimed
CN-117801373-A Preparation method and application of functionalized titanium dioxide 河南龙兴钛业科技股份有限公司 2024-04-02 CN claimed
US-20210087336-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIVERSITY HEALTH NETWORK (CA) 2021-03-25 US claimed
EP-3658625-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO University Health Network (CA) 2020-06-03 EP claimed
CN-110997810-A Electrically conductive biomaterials comprising benzoic acid based polymers for enhancing tissue conductivity in vitro and in vivo 大学健康网络 2020-04-10 CN claimed
CN-106011190-B Preparation method of natural p-aminobenzoic acid and derivatives thereof 福建师范大学 2020-02-07 CN claimed
WO-2019018942-A1 CONDUCTIVE BENZOIC ACID BASED POLYMER CONTAINING BIOMATERIAL FOR ENHANCEMENT OF TISSUE CONDUCTION IN VITRO AND IN VIVO UNIVERSITY HEALTH NETWORK (CA) 2019-01-31 WO claimed
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LTD (IE) 2018-03-08 US claimed
CN-105705488-A Acetylcholinesterase inhibitor compounds and 5HT4 serotonergic receptor agonisis, with promnesia effect, methods for the preparation thereof and pharmaceutical compositions containing same 卡昂大学 2016-06-22 CN claimed
EP-1910275-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD Giuliani International Limited (IE) 2008-04-16 EP claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
CN-101040028-A Photocrosslinkable materials ROLIC AG (CH) 2007-09-19 CN claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
WO-2007010514-A2 COMPOUNDS AND THEIR SALTS SPECIFIC TO THE PPAR RECEPTORS AND THE EGF RECEPTORS AND THEIR USE IN THE MEDICAL FIELD GIULIANI INTERNATIONAL LIMITED (IE) 2007-01-25 WO claimed
US-20060110743-A1 Drug evolution: drug design at hot spots KONISHI YASUO 2006-05-25 US claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
WO-2003016615-A1 SINGLE BATH PROCESS FOR BLEACHING AND DYEING TEXTILES NOVOZYMES NORTH AMERICA, INC. (US) 2003-02-27 WO claimed
WO-2002095393-A2 DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2002-11-28 WO claimed
US-4036951-A SUNSCREEN AGENTS SYNERGISTICS, INC. (US) 1977-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 ALDH1A1 1606/4885MAPT 467/4885KDM4E 844/4885
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG ALDH1A1 530/4885MAPT 4369/4885KDM4E 4341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.