Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPID | Q08752 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPIB | P23284 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | PPIG | Q13427 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19963575 | 0.88 | THRB (0.42) | THRBTSHRALDH1A1PPIDPOLB | |
| SCHEMBL2195083 | 0.85 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL22663637 | 0.84 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL17298819 | 0.83 | THRB (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL11837742 | 0.82 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL25765284 | 0.81 | THRB (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL17124679 | 0.81 | THRB (0.44) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14582190 | 0.80 | TSHR (0.50) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10093567 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13590585 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510041-B1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-31 | — | — | EP | disclosed |