Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422734 | 0.84 | NOTUM (0.47) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL14914823 | 0.84 | NOTUM (0.47) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL25564365 | 0.82 | NOTUM (0.46) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL22655542 | 0.82 | KDM4E (0.55) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL1110800 | 0.78 | NOTUM (0.58) | NOTUMKDM4EL3MBTL1LMNAGAA | |
| SCHEMBL24901671 | 0.78 | NOTUM (0.49) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL2240748 | 0.77 | NOTUM (0.59) | NOTUMKDM4EL3MBTL1LMNAGAA | |
| SCHEMBL25902171 | 0.77 | PDE4D (0.41) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL22168072 | 0.76 | KDM4E (0.48) | NOTUMPOLBKDM4EL3MBTL1LMNA | |
| SCHEMBL26122367 | 0.76 | KDM4E (0.63) | NOTUMPOLBKDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |