Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300017 | 0.90 | KMT2A (0.44) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL25902169 | 0.84 | KMT2A (0.49) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL25902174 | 0.83 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL25903519 | 0.82 | PDE4D (0.43) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL26076212 | 0.81 | EPHX2 (0.41) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL31336127 | 0.81 | EPHX2 (0.41) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL22655542 | 0.79 | KDM4E (0.55) | POLBKDM4ELMNAGAANFKB1 | |
| SCHEMBL31160144 | 0.79 | PDE5A (0.40) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL29633602 | 0.79 | HSD17B10 (0.45) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL23534443 | 0.77 | NOTUM (0.47) | PDE4DPDE4APDE4BPDE4CEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2024-02-29 | — | — | US | disclosed |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | BioAge Labs, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-08-03 | — | — | US | disclosed |
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | BioAge Labs, Inc. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242528-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | PDE4D 1063/4885PDE4A 438/4885PDE4B 655/4885 |
| US-20240067648-A1 | N-OXIDE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, CASP1 | PDE4D 1063/4885PDE4A 438/4885PDE4B 655/4885 |
| US-11787805-B2 | N-oxide inhibitors of NLRP3 inflammasome | NLRP3, NOD1, CASP1 | PDE4D 1063/4885PDE4A 438/4885PDE4B 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.