Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855473 | 0.77 | ACHE (0.42) | CYP4F2CYP4A11KIF11TSHRAKR1B1 | |
| SCHEMBL11029542 | 0.75 | CYP4F2 (0.56) | CYP4F2CYP4A11SIGMAR1EPHX2KCNH2 | |
| SCHEMBL2447332 | 0.75 | EPHX2 (0.50) | CYP4F2CYP4A11EPHX2KIF11PDE2A | |
| SCHEMBL2239493 | 0.74 | CYP4F2 (0.39) | CYP4F2CYP4A11SIGMAR1EPAS1KCNH2 | |
| SCHEMBL11032847 | 0.72 | NOTUM (0.38) | CYP4F2CYP4A11EPHX2NOTUM | |
| SCHEMBL2241890 | 0.71 | MBOAT4 (0.43) | CYP4F2CYP4A11EPHX2EPAS1KIF11 | |
| SCHEMBL25564368 | 0.71 | KAT7 (0.39) | — | |
| SCHEMBL16961827 | 0.71 | CYP4F2 (0.42) | CYP4F2CYP4A11SIGMAR1EPHX2KCNH2 | |
| SCHEMBL25367417 | 0.70 | NOTUM (0.39) | NOTUMKCNN4 | |
| SCHEMBL30694799 | 0.70 | NOTUM (0.39) | NOTUMKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |