Sugi Predict

Sugi Predict / Compounds / SCHEMBL25564615

SCHEMBL25564615

SCHEMBL25564615

CC(C)(C)c1cc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2cnc[nH]2)no1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29213101 1.00 CSF1R (1.00) CSF1R
SCHEMBL25564489 0.92 CSF1R (0.84) CSF1R
SCHEMBL29213097 0.87 CSF1R (1.00) CSF1R
SCHEMBL25564419 0.87 CSF1R (1.00) CSF1R
SCHEMBL25184579 0.86 CSF1R (1.00) CSF1R
SCHEMBL25184575 0.86 CSF1R (1.00) CSF1R
SCHEMBL29213102 0.85 CSF1R (1.00) CSF1R
SCHEMBL30860263 0.85 CSF1R (1.00) CSF1R
SCHEMBL25564495 0.85 CSF1R (1.00) CSF1R
SCHEMBL29213100 0.84 CSF1R (0.79) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999221-A 6-substituted indolone derivative, preparation method and medical application thereof 南京中医药大学 2022-02-01 — — CN claimed
CN-113999221-B 6-substituted indolone derivative and medical application thereof 南京中医药大学 2024-04-05 — — CN disclosed
WO-2023078207-A1 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 南京中医药大学 2023-05-11 — — WO disclosed
CN-113999221-A 6-substituted indolone derivative, preparation method and medical application thereof 南京中医药大学 2022-02-01 — — CN disclosed
Send feedback