Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.84 |
| ▸ | FLT3 | P36888 | 7/20 | 0.66 |
| ▸ | KDR | P35968 | 5/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.66 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.66 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.66 |
| ▸ | KIT | P10721 | 5/20 | 0.58 |
| ▸ | FLT4 | P35916 | 5/20 | 0.58 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.56 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564419 | 0.91 | CSF1R (1.00) | CSF1RFLT3KDRPDGFRBKIT | |
| SCHEMBL29213097 | 0.91 | CSF1R (1.00) | CSF1RFLT3KDRPDGFRBKIT | |
| SCHEMBL25564489 | 0.87 | CSF1R (0.84) | CSF1R | |
| SCHEMBL25567495 | 0.80 | CSF1R (0.70) | CSF1R | |
| SCHEMBL15328029 | 0.80 | FLT3 (1.00) | FLT3KDRPDGFRBAURKBAURKA | |
| SCHEMBL15328030 | 0.79 | FLT3 (1.00) | FLT3KDRPDGFRBAURKBAURKA | |
| SCHEMBL18060032 | 0.79 | FLT3 (1.00) | FLT3KDRPDGFRBAURKBAURKA | |
| SCHEMBL15339438 | 0.79 | FLT3 (0.80) | FLT3KDRPDGFRBAURKBAURKA | |
| SCHEMBL29213101 | 0.79 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25564615 | 0.79 | CSF1R (1.00) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |