Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.65 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.65 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.62 |
| ▸ | SRC | P12931 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.60 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.58 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.58 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069787 | 0.99 | P2RX3 (0.66) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL12932298 | 0.99 | P2RX3 (0.66) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL1062774 | 0.99 | P2RX3 (0.66) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL8616900 | 0.92 | P2RY1 (0.66) | POLBP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL21132954 | 0.90 | POLB (0.62) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL29352481 | 0.90 | POLB (0.81) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL2508784 | 0.90 | POLB (0.81) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL77641 | 0.90 | POLB (0.81) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL31211719 | 0.90 | POLB (0.81) | POLBP2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL703733 | 0.89 | POLB (0.80) | POLBP2RX3P2RX1P2RX2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086557-A1 | NUCLEOSIDES FOR THE TREATMENT OF DNA VIRUS INFECTIONS | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |