⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929899 | 0.78 | ESR2 (0.36) | — | |
| SCHEMBL23929897 | 0.78 | ESR2 (0.36) | — | |
| SCHEMBL23930135 | 0.76 | ESR2 (0.37) | — | |
| SCHEMBL25565196 | 0.76 | ESR2 (0.34) | — | |
| SCHEMBL23930130 | 0.76 | ESR2 (0.37) | — | |
| SCHEMBL23957657 | 0.75 | ESR2 (0.35) | — | |
| SCHEMBL23930120 | 0.75 | DGAT1 (0.43) | — | |
| SCHEMBL30257922 | 0.75 | DGAT1 (0.43) | — | |
| SCHEMBL23930122 | 0.75 | DGAT1 (0.43) | — | |
| SCHEMBL23929961 | 0.72 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159523-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |