SCHEMBL23957657

SCHEMBL23957657

C[C@@H](c1ccc(N/C=C(/F)C=N)nc1)N(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.35
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23957720 0.82 PDE4A (0.30)
SCHEMBL25565196 0.81 ESR2 (0.34) ESR2DGAT1
SCHEMBL23929897 0.77 ESR2 (0.36) ESR2DGAT1
SCHEMBL23929899 0.77 ESR2 (0.36) ESR2DGAT1
SCHEMBL23957645 0.77
SCHEMBL25565202 0.75
SCHEMBL23930135 0.75 ESR2 (0.37) ESR2DGAT1
SCHEMBL23930130 0.75 ESR2 (0.37) ESR2DGAT1
SCHEMBL23930120 0.74 DGAT1 (0.43) ESR2DGAT1
SCHEMBL23930122 0.74 DGAT1 (0.43) ESR2DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4141003-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF Shenzhen Zhongge Biological Technology Co., Ltd. (CN) 2023-03-01 EP disclosed
WO-2021213476-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF 深圳晶泰科技有限公司 (CN) 2021-10-28 WO disclosed