Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25562919 | 0.84 | NR1H3 (0.33) | SMN1; SMN2ALDH1A1HTTPRKDCNR1H3 | |
| SCHEMBL25564780 | 0.82 | OPRK1 (0.56) | OPRL1OPRK1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL21904166 | 0.81 | OPRL1 (0.44) | OPRL1OPRK1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL21904556 | 0.81 | OPRK1 (0.41) | OPRL1OPRK1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL17983437 | 0.77 | OPRM1 (0.53) | OPRL1OPRK1OPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14367669 | 0.75 | MEN1 (0.39) | ALDH1A1TP53POLBNR1H3 | |
| SCHEMBL24219918 | 0.74 | BACE1 (0.38) | OPRL1OPRK1OPRM1OPRD1EZH2 | |
| SCHEMBL23591212 | 0.74 | SMN1; SMN2 (0.45) | OPRL1OPRK1OPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL21904416 | 0.74 | CALCRL (0.44) | OPRL1OPRK1OPRM1OPRD1ALDH1A1 | |
| SCHEMBL28372584 | 0.74 | PRKDC (0.44) | EZH2PRKDCCALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159465-A1 | IMMUNOMODULATOR | HITGEN INC. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159465-A1 | IMMUNOMODULATOR | IL2, IL17A, IL2RA | OPRL1 2086/4885OPRK1 1292/4885OPRM1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.