SCHEMBL25565486

SCHEMBL25565486

BC1c2c(ccc(OC)c2F)-c2ccc(OC)c(F)c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.35
HTR2C P28335 4/20 0.35
HTR2B P41595 4/20 0.35
CYP3A4 P08684 2/20 0.33
TUBB1 Q9H4B7 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
CA2 P00918 2/20 0.32
KDM1A O60341 2/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP4B1 P13584 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP3A5 P20815 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25565497 0.91 TUBB1 (0.34) HTR2AHTR2CHTR2BCYP3A4TUBB1
SCHEMBL14015536 0.73 GRM8 (0.43) CYP3A4TUBB1CYP17A1CYP11B1CYP11B2
SCHEMBL15682035 0.72 CA2 (0.47) CYP3A4TUBB1CA2ADRA1ACA12
SCHEMBL25565492 0.72 SYK (0.31)
SCHEMBL19621894 0.72 KDM4E (0.39) TUBB1KDM1A
SCHEMBL13039547 0.72 HTR2A (0.31) HTR2AHTR2CHTR2B
SCHEMBL25565488 0.70 PDE4A (0.33)
SCHEMBL25565491 0.70 PDE4A (0.30)
SCHEMBL25565496 0.69 PDE4B (0.38) HTR2AHTR2CHTR2B
SCHEMBL19621835 0.69 CTSL (0.39) HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11788010-B2 Liquid crystal composition and liquid crystal display device comprising the same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-17 US disclosed
US-20230159826-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-25 US disclosed