Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25571244 | 0.89 | CARM1 (0.47) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL4374852 | 0.81 | GNAO1 (0.38) | GNAO1 | |
| SCHEMBL18497449 | 0.80 | HRH3 (0.46) | SIGMAR1GNAO1HRH3 | |
| SCHEMBL4384231 | 0.80 | GNAO1 (0.41) | SIGMAR1GNAO1HRH1HRH3 | |
| SCHEMBL4667680 | 0.80 | GNAO1 (0.41) | SIGMAR1GNAO1HRH3 | |
| SCHEMBL25666698 | 0.79 | SIGMAR1 (0.46) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL27108004 | 0.79 | CARM1 (0.46) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL4667710 | 0.79 | GNAO1 (0.43) | GNAO1HRH1HRH3 | |
| SCHEMBL23828682 | 0.77 | CARM1 (0.60) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL24319796 | 0.76 | GNAO1 (0.44) | CARM1PRMT6PRMT1PRMT8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |