SCHEMBL25565744

SCHEMBL25565744

CC(C)Oc1cc2c(cc1OC(C)C)C1(C)CCC2(C)c2cc(OC(C)C)c(OC(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.33
SPIN1 Q9Y657 1/20 0.33
TLR8 Q9NR97 1/20 0.33
ACHE P22303 1/20 0.33
CSNK2A1 P68400 2/20 0.31
ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16673949 0.75 CYP3A4 (0.44) EHMT2ACHE
SCHEMBL25565740 0.74 EHMT2 (0.32) EHMT2SPIN1ACHE
SCHEMBL23071760 0.68 ALDH1A1 (0.38) TLR8ACHECSNK2A1
SCHEMBL12729988 0.65 CA1 (0.36) ACHE
SCHEMBL11544312 0.64 TLR8 (0.42) TLR8ACHECSNK2A1
SCHEMBL28844605 0.64 MAPT (0.43) TLR8CSNK2A1
SCHEMBL30131979 0.64 ALDH1A1 (0.36)
SCHEMBL21440629 0.64 PTK2 (0.44)
SCHEMBL9988792 0.64 ALDH1A1 (0.36)
SCHEMBL4460699 0.64 KCNH2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 EHMT2 3340/4885SPIN1 4490/4885TLR8 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.