Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962643 | 0.86 | HTR1D (0.49) | CHRM4CHRM1GAAMAPTKDM4E | |
| SCHEMBL4562943 | 0.86 | HTR1D (0.49) | CHRM4CHRM1GAAMAPTKDM4E | |
| Iodide SCHEMBL4080888 | 0.85 | HTR1D (0.48) | GAAMAPTKDM4EHTR1DHTR1B | |
| SCHEMBL10036163 | 0.77 | HTR1D (0.49) | CHRM4CHRM1HTR1DHTR1BDRD2 | |
| SCHEMBL13723802 | 0.77 | HTR1D (0.43) | GAAMAPTKDM4EHTR1DHTR1B | |
| SCHEMBL6924205 | 0.76 | ABCB1 (0.43) | CHRM4CHRM1MAPTKDM4ECHRM2 | |
| SCHEMBL20899575 | 0.76 | MAPT (0.47) | GAAMAPTKDM4ETRPC6TP53 | |
| SCHEMBL17631444 | 0.75 | CHRM4 (0.47) | CHRM4CHRM1CHRM2HTR1DHTR1B | |
| SCHEMBL23978364 | 0.72 | ADRA2A (0.47) | HTR1DHTR1BDRD2 | |
| SCHEMBL10127415 | 0.72 | FGFR3 (0.50) | MAPTKDM4ECHRM2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094310-A1 | PYRAZOLOTRIAZINE DERIVATIVES USEFUL AS CDK9 INHIBITORS | ORIGENIS GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |