Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565752 | 0.84 | MAPT (0.42) | KDM4EGAAMAPT | |
| SCHEMBL29974417 | 0.80 | QDPR (0.46) | KDM4EQDPRSLC6A4 | |
| SCHEMBL30962657 | 0.79 | SLC6A4 (0.57) | MAPTQDPRSLC6A4 | |
| SCHEMBL21350146 | 0.79 | SLC6A4 (0.48) | KDM4EGAAMAPTQDPRSLC6A4 | |
| SCHEMBL30594672 | 0.79 | SLC6A4 (0.48) | KDM4EGAAMAPTQDPRSLC6A4 | |
| SCHEMBL7033282 | 0.78 | QDPR (0.56) | KDM4EGAAMAPTQDPRSLC6A4 | |
| SCHEMBL11986944 | 0.78 | SLC6A4 (0.42) | KDM4EQDPRSLC6A4NOS1 | |
| Hydrochloric Acid SCHEMBL7030177 | 0.78 | QDPR (0.56) | KDM4EGAAMAPTQDPRSLC6A4 | |
| SCHEMBL5010128 | 0.77 | SLC6A4 (0.48) | KDM4EQDPRSLC6A4 | |
| SCHEMBL30962901 | 0.77 | KDM4E (0.49) | KDM4EMAPTQDPRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023094310-A1 | PYRAZOLOTRIAZINE DERIVATIVES USEFUL AS CDK9 INHIBITORS | ORIGENIS GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |