Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18330367 | 0.81 | ALDH1A1 (0.56) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL15224180 | 0.77 | NPC1 (0.79) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL2606045 | 0.77 | ALDH1A1 (0.60) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL15224251 | 0.77 | NPC1 (0.71) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL24491912 | 0.77 | ALDH1A1 (0.51) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL8284598 | 0.76 | ALDH1A1 (0.64) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL3736947 | 0.76 | MAOA (0.35) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL19884749 | 0.76 | NPC1 (0.76) | ALDH1A1NPC1MEN1KMT2AHPGD | |
| SCHEMBL19884750 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1MEN1KMT2ALMNA | |
| SCHEMBL13043882 | 0.75 | HRH3 (0.39) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |