Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330311 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9KDM4EMEN1 | |
| SCHEMBL2559591 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9KDM4EMEN1 | |
| SCHEMBL10290933 | 0.80 | KDM4E (0.41) | ALDH1A1CYP1A2CYP2C9KDM4ERAB9A | |
| SCHEMBL2562682 | 0.78 | ENPP2 (0.52) | ALDH1A1CYP1A2CYP2C9KDM4EMEN1 | |
| SCHEMBL14416566 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C9KDM4ERAB9A | |
| SCHEMBL21396 | 0.77 | ENPP2 (0.44) | ALDH1A1MEN1KMT2AHSD17B10LPL | |
| SCHEMBL17316744 | 0.76 | SLC6A4 (0.43) | ALDH1A1CYP1A2CYP2C9KDM4ERAB9A | |
| SCHEMBL11894322 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9KDM4EMEN1 | |
| SCHEMBL12126099 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C9KDM4ERAB9A | |
| SCHEMBL12128121 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4EMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |