Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30730520 | 1.00 | KDM4E (0.50) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL27448122 | 0.82 | KDM4E (0.48) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL3803604 | 0.82 | KDM4E (0.48) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL105808 | 0.78 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL598345 | 0.78 | MEN1 (0.69) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL31211720 | 0.78 | CYP19A1 (0.66) | KDM4EHPGDSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL1125330 | 0.78 | ALDH1A1 (0.47) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1125249 | 0.78 | ERCC5 (0.55) | KDM4EHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL767241 | 0.78 | ERCC5 (0.55) | HPGDMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1125179 | 0.78 | PTPN1 (0.55) | HPGDALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090028751-A1 | ANTI-MICROBIAL TIME CARD | ROBBINS GLENN | 2009-01-29 | — | — | US | claimed |
| US-6995203-B2 | Flame retardant polymer compositions | THE BOEING COMPANY (US) | 2006-02-07 | — | — | US | claimed |
| US-20240336868-A1 | COMPOSITIONS COMPRISING ADAMANTYL ESTER-CONTAINING COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2024-10-10 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| CN-107141299-B | Substituted pyrrole chromone compound and application thereof | 中山大学 | 2020-03-13 | — | — | CN | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| CN-105777725-B | The application of 3- (2- furyls) chromogen ketone compounds and preparation method thereof and plant epiphyte resisting | 陕西师范大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-107141299-A | A kind of substituted azole chromogen ketone compounds and its application | 中山大学 | 2017-09-08 | — | — | CN | disclosed |
| CN-105777725-A | 3-(2-furyl) chromone compound, preparation method thereof and application in resisting plant fungi | 陕西师范大学 | 2016-07-20 | — | — | CN | disclosed |
| US-20020128522-A1 | Process for the preparation of 4,4' -dihalogen-o-hydroxydiphenyl compounds | TEODORO ARMANDO DI (DE) | 2002-09-12 | — | — | US | disclosed |
| US-6346260-B1 | HETEROCYCLIC ALKYLENEDIONE PHENOLS AND ALKYLENEDIONE PHENYL PHENOL | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| US-6346260-B1 | HETEROCYCLIC ALKYLENEDIONE PHENOLS AND ALKYLENEDIONE PHENYL PHENOL | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| CN-1321142-A | Process for preparation of 4,4'-dihalo-o-hydroxydiphenyl compounds | CIBA SPECIALTY CHEMICLAS HOLDI (CH) | 2001-11-07 | — | — | CN | disclosed |
| EP-1119540-A1 | PROCESS FOR THE PREPARATION OF 4,4'-DIHALOGEN-O-HYDROXYDIPHENYL COMPOUNDS | Ciba SC Holding AG (CH) | 2001-08-01 | — | — | EP | disclosed |
| EP-1074179-A3 | Microbicidal active ingredients | Ciba SC Holding AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| EP-1074179-A2 | Microbicidal active ingredients | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| EP-1074179-A2 | Microbicidal active ingredients | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| WO-2000020366-A1 | PROCESS FOR THE PREPARATION OF 4,4'-DIHALOGEN-O-HYDROXYDIPHENYL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128522-A1 | Process for the preparation of 4,4' -dihalogen-o-hydroxydiphenyl compounds | DDT, CYP2F1, CYP4X1 | KDM4E 797/4885HPGD 861/4885SMN1; SMN2 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.