SCHEMBL105808

SCHEMBL105808

O=C(CO)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
HPGD P15428 6/20 0.58
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
HMGB1 P09429 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
CA14 Q9ULX7 1/20 0.58
MAPT P10636 4/20 0.56
TSHR P16473 4/20 0.56
HSD17B10 Q99714 2/20 0.56
CYP19A1 P11511 1/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036274 0.86 LIG1 (0.61) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL598345 0.85 MEN1 (0.69) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL31211720 0.85 CYP19A1 (0.66) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL1878649 0.84 TERT (0.52) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL7826271 0.83 KDM4E (0.56) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL1701142 0.81 PTPN1 (0.57) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL19809218 0.81 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL6129338 0.81 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL12302413 0.81 KDM4E (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL7819309 0.81 HPGD (0.55) KDM4EHPGDALDH1A1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055051-A1 Compound with anti-tumor activity, preparation method therefor, and use thereof OCEAN UNIV CHINA (CN) 2026-02-26 US claimed
US-20250231190-A1 ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING THE JOHNS HOPKINS UNIVERSITY 2025-07-17 US claimed
WO-2025092541-A1 LITHIUM EXTRACTION RESIN STRUCTURE, PREPARATION, AND USE 北京索特莱克科技发展有限公司 2025-05-08 WO claimed
CN-221016077-U 2,6 Dihydroxy acetophenone acylation reaction system 曲靖常宜联合科技有限公司 2024-05-28 CN claimed
CN-221016054-U 2,6 Dihydroxyacetophenone hydrolysis reaction device 曲靖常宜联合科技有限公司 2024-05-28 CN claimed
WO-2024031970-A1 COMPOUND WITH ANTI-TUMOR ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国海洋大学 2024-02-15 WO claimed
US-20240003899-A1 METHOD FOR DETECTION OF ANALYTES IN A SINGLE TISSUE SAMPLE FROM ITO SLIDES USING MSI-LCM ACADEMISCH ZIEKENHUIS MAASTRICHT (NL) 2024-01-04 US claimed
CN-115427514-B Resin composition, light-shielding film, and substrate with partition wall 东丽株式会社 2024-01-02 CN claimed
US-11827605-B2 Isoquinoline compounds and their use in treating AhR imbalance Dermavant Sciences GmbH (CH) 2023-11-28 US claimed
CN-116655577-B Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof 山东中医药大学 2023-11-14 CN claimed
WO-2003030845-A1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
WO-1996022077-A1 ARYL KETONES FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-07-25 WO claimed
US-5508451-A Process for the preparation of dialkali metal cromoglycates HOECHST CELANESE CORPORATION (US) 1996-04-16 US claimed
US-5506348-A COMPOSITION CONTAINING AMMONIUM SALT OF ORGANIC OR INORGANIC ACID, HYDROXY SUBSTITUTED PHENONE, HIGH MOLECULAR WEIGHT COMPOUND CIBA-GEIGY CORPORATION (US) 1996-04-09 US claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
EP-0612994-A2 Matrix for matrix-assisted laser desorption mass spectroscopy CIBA-GEIGY AG (CH) 1994-08-31 EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055051-A1 Compound with anti-tumor activity, preparation method therefor, and use thereof RCC2, WEE2, MET KDM4E 657/4885HPGD 2452/4885ALDH1A1 838/4885
US-11827605-B2 Isoquinoline compounds and their use in treating AhR imbalance AHR, ARNT, HRH1 KDM4E 2743/4885HPGD 123/4885ALDH1A1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.