Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | DHPS | P49366 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566469 | 0.83 | CMA1 (0.45) | TRPV1MAPTHTTEPHX2CRBN | |
| SCHEMBL25564759 | 0.80 | MAPK14 (0.58) | NPC1RAB9AMEN1KMT2ACSF1R | |
| SCHEMBL10576398 | 0.80 | CMA1 (0.49) | TRPV1MAPTMEN1KMT2ACRBN | |
| SCHEMBL25567247 | 0.79 | MAPK14 (0.59) | TRPV1CSF1R | |
| SCHEMBL25566191 | 0.79 | MAPK14 (0.58) | MAPTLMNACSF1R | |
| SCHEMBL3662896 | 0.79 | CRBN (0.52) | HTTSMN1; SMN2CRBNTLK2 | |
| SCHEMBL6125101 | 0.79 | AHR (0.56) | TRPV1MEN1KMT2ACRBNDHPS | |
| SCHEMBL3654523 | 0.78 | BRD4 (0.48) | TRPV1MEN1KMT2ACRBNTLK2 | |
| SCHEMBL25566649 | 0.77 | CA12 (0.54) | TRPV1KIF11 | |
| SCHEMBL396156 | 0.77 | DDX3X (0.59) | TRPV1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |