Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566713 | 0.74 | CSF1R (0.52) | CSF1RDDR1TRPV1MEN1KMT2A | |
| SCHEMBL19411114 | 0.63 | CYP1A2 (0.75) | CSF1RMEN1KMT2ALMNAMAPT | |
| SCHEMBL19480627 | 0.63 | CYP2C9 (0.57) | CSF1RMEN1KMT2ALMNAMAPT | |
| SCHEMBL13105727 | 0.61 | HTR2A (0.44) | CSF1RMEN1KMT2AHTR2AUTS2R | |
| SCHEMBL19957410 | 0.58 | NPSR1 (0.65) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL19957442 | 0.58 | NPSR1 (0.51) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL25566737 | 0.58 | MAPT (0.51) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1011920 | 0.58 | POLB (0.63) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL29277354 | 0.58 | ALDH1A1 (0.43) | MEN1KMT2AHTR2ALMNAMAPT | |
| SCHEMBL25566598 | 0.57 | KDR (0.51) | CSF1RTRPV1EPHX2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |