Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25566737 | 0.84 | MAPT (0.51) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL25566598 | 0.83 | KDR (0.51) | CSF1REPHX2TRPV1BRAF | |
| SCHEMBL25566268 | 0.81 | KDR (0.65) | TRPV1 | |
| SCHEMBL22425121 | 0.77 | MAPT (0.53) | RAB9AMEN1KMT2APOLB | |
| SCHEMBL25566469 | 0.76 | CMA1 (0.45) | CSF1REPHX2TRPV1 | |
| SCHEMBL25566378 | 0.76 | CSF1R (0.52) | CSF1REPHX2TRPV1 | |
| SCHEMBL25566546 | 0.76 | TRPV1 (0.57) | CSF1REPHX2TRPV1NPC1RAB9A | |
| SCHEMBL22424926 | 0.75 | MAPT (0.51) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL3598229 | 0.74 | KIF11 (0.68) | EPHX2TRPV1RAB9AMEN1KMT2A | |
| SCHEMBL25566709 | 0.74 | CSF1R (0.41) | CSF1REPHX2TRPV1DDR1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |