Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.35 |
| ▸ | KAT7 | O95251 | 3/20 | 0.35 |
| ▸ | KAT6B | Q8WYB5 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.30 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565052 | 0.88 | — | — | |
| SCHEMBL25565025 | 0.88 | HTR1A (0.33) | KAT6AKAT7KAT6BHTR1AADRA1D | |
| SCHEMBL25561774 | 0.82 | KAT6A (0.55) | KAT6AKAT7KAT6B | |
| SCHEMBL30360835 | 0.82 | KAT6A (0.55) | KAT6AKAT7KAT6B | |
| SCHEMBL25562267 | 0.81 | KAT6A (0.49) | KAT6AKAT7KAT6B | |
| SCHEMBL30360809 | 0.81 | KAT6A (0.49) | KAT6AKAT7KAT6B | |
| SCHEMBL25564467 | 0.80 | KAT6A (0.42) | KAT6AKAT7KAT6BSGMS1SGMS2 | |
| SCHEMBL30360831 | 0.78 | KAT6A (0.53) | KAT6AKAT7KAT6B | |
| SCHEMBL25562126 | 0.78 | KAT6A (0.53) | KAT6AKAT7KAT6B | |
| SCHEMBL30360821 | 0.76 | KAT6A (0.48) | KAT6AKAT7KAT6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |