SCHEMBL25566977

SCHEMBL25566977

N#Cc1ccc2c(c1)C1c3ccccc3C2c2cc(C#N)c(I)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
CHRND Q07001 1/20 0.36
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
DRD2 P14416 5/20 0.32
DRD3 P35462 5/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
DYRK1A Q13627 1/20 0.32
SLC6A4 P31645 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25566982 0.95 CHRNA1 (0.39) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL25567063 0.95 CHRNA1 (0.39) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL25566854 0.90 KDM4E (0.33) KDM4EALDH1A1GAACA1CA2
SCHEMBL25566903 0.90 KDM4E (0.33) KDM4EALDH1A1GAACA1CA2
SCHEMBL25566853 0.85 CHRNA1 (0.46) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL25566981 0.81 XDH (0.35) DYRK1ATTRALB
SCHEMBL25567065 0.81 XDH (0.35) DYRK1ATTRALB
SCHEMBL24791025 0.79 CHRNA1 (0.50) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL19207348 0.79 CHRNA1 (0.50) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL25567820 0.77 STS (0.39) GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094412-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-01 WO disclosed