Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556734 | 1.00 | MEN1 (0.49) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL15329654 | 0.71 | CYP3A4 (0.52) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL15329656 | 0.71 | CYP3A4 (0.52) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL2559162 | 0.69 | MAPT (0.57) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL2559161 | 0.69 | MAPT (0.57) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL15332212 | 0.67 | LMNA (0.56) | MEN1MAPTKMT2AMAOBMAOA | |
| SCHEMBL15332213 | 0.67 | LMNA (0.56) | MEN1MAPTKMT2AMAOBMAOA | |
| SCHEMBL2554718 | 0.66 | MEN1 (1.00) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL2554721 | 0.66 | MEN1 (1.00) | MEN1MAPTKMT2AMAOBPTPN1 | |
| SCHEMBL2556028 | 0.64 | MAPT (0.57) | MEN1MAPTKMT2AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |