SCHEMBL25567463

SCHEMBL25567463

Clc1cccc2c1sc1cccc(-c3ccc(-c4cccc5ccccc45)cc3)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2A6 P11509 2/20 0.42
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP1A1 P04798 2/20 0.38
CYP1B1 Q16678 2/20 0.38
CYP2C19 P33261 2/20 0.38
LIMK1 P53667 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24778323 0.89 CYP2A6 (0.46) CYP1A2CYP2A6CYP1A1CYP1B1CYP2C19
SCHEMBL25569776 0.88 LIMK1 (0.46) CYP1A2CYP2A6LIMK1ALOX5MCL1
SCHEMBL24969647 0.88 LIMK1 (0.48) CYP1A2CYP2A6LIMK1ALOX5MCL1
SCHEMBL23765008 0.82 PLK4 (0.35) CYP1A2CYP2A6HDAC8HDAC6CYP1A1
SCHEMBL22701889 0.81 ALOX5 (0.46) CA12CA1CA2CA9CYP1A2
SCHEMBL22129988 0.80 GPR3 (0.43) CYP1A2CYP2A6KDM4EALDH1A1RAB9A
SCHEMBL24777850 0.78 CYP2A6 (0.47) CA12CA1CA2CA9CYP1A2
SCHEMBL23427851 0.78 CA12 (0.41) CA12CA1CA2CA9CYP1A2
SCHEMBL23981335 0.78 CYP1A2 (0.50) CYP1A2CYP2A6HDAC8HDAC6CYP1A1
SCHEMBL21096860 0.78 ALOX5 (0.38) CA12CA1CA2CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023096209-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-06-01 WO disclosed