SCHEMBL25567622

SCHEMBL25567622

CC1C2CCC1CC(c1ccccc1)C(O)C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A3 Q01959 2/20 0.40
▸ MAOB P27338 8/20 0.39
▸ MAOA P21397 7/20 0.39
▸ KDM1A O60341 5/20 0.39
▸ CYP2C19 P33261 4/20 0.39
▸ CYP2B6 P20813 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ TAAR1 Q96RJ0 2/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ HTR1A P08908 1/20 0.39
▸ ADRA2A P08913 1/20 0.39
▸ CYP2A6 P11509 1/20 0.39
▸ SLC6A2 P23975 1/20 0.39
▸ HTR2C P28335 1/20 0.39
▸ ADRA1A P35348 1/20 0.39
▸ DRD3 P35462 1/20 0.39
▸ KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5359549 0.80 MAOB (0.56) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL12953786 0.80 MAOB (0.56) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL1719673 0.80 MAOB (0.56) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL3632621 0.79 MAOB (0.43) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL27488357 0.74 MAOB (0.42) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL24820970 0.70 SLC18A3 (0.45) MAOBMAOACYP1A2CYP2D6CYP2C9
SCHEMBL10914783 0.69 MAOB (0.48) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL20473102 0.69 MAOB (0.48) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL13060621 0.68 MAOB (0.43) SLC6A3MAOBMAOAKDM1ACYP2C19
SCHEMBL21893525 0.68 MAOB (0.43) SLC6A3MAOBMAOAKDM1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 SLC6A3 4129/4885MAOB 1788/4885MAOA 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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