Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30423961 | 1.00 | CNR2 (0.44) | CNR2CTSACOMTMEN1KMT2A | |
| SCHEMBL25207848 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL12468522 | 0.78 | CNR2 (0.54) | CNR2CTSAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30423687 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25256041 | 0.76 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25253968 | 0.76 | CNR2 (0.51) | CNR2CTSAEGFRKDM4EALDH1A1 | |
| SCHEMBL25241086 | 0.74 | LMNA (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL25218899 | 0.73 | LMNA (0.54) | CTSAMEN1KMT2AEGFRKDM4E | |
| SCHEMBL11711016 | 0.71 | CA12 (0.46) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29735324 | 0.70 | PLAU (0.54) | COMTEGFRALDH1A1USP30KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |