Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219371 | 0.88 | CYP3A4 (0.37) | NPSR1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL28548480 | 0.79 | — | — | |
| SCHEMBL11006305 | 0.78 | NPSR1 (0.38) | NPSR1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL13954119 | 0.78 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16369860 | 0.78 | FFAR3 (0.48) | NPSR1CYP2C19LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7114208 | 0.77 | NPSR1 (0.37) | NPSR1CYP3A4CYP2C9PKMCYP2C19 | |
| SCHEMBL1928676 | 0.77 | — | — | |
| SCHEMBL17958 | 0.77 | NPSR1 (0.52) | NPSR1CYP3A4MEN1KMT2ACYP4F2 | |
| SCHEMBL20221227 | 0.76 | ALDH1A1 (0.35) | PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL20837313 | 0.76 | DGAT1 (0.33) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556068-A1 | P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011124930-A1 | P38 MAP KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2011-10-13 | — | — | WO | disclosed |