Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926705 | 0.85 | ALDH1A1 (0.47) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL18624221 | 0.85 | MAPT (0.41) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL2559785 | 0.84 | KDM4E (0.47) | ALDH1A1KDM4EATML3MBTL1CYP11B2 | |
| SCHEMBL2556764 | 0.84 | SLC22A12 (0.38) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL18613085 | 0.84 | ALDH1A1 (0.37) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL18593626 | 0.81 | ALDH1A1 (0.36) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL18639317 | 0.81 | MAPT (0.48) | ALDH1A1KDM4EL3MBTL1CYP11B2CYP11B1 | |
| SCHEMBL2557956 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL13353920 | 0.78 | POLB (0.41) | ALDH1A1POLBKDM4EATML3MBTL1 | |
| SCHEMBL30301263 | 0.77 | ALDH1A1 (0.37) | ALDH1A1POLBKDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422287-B2 | Bridged triarylamines and -phosphines as materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422287-B2 | Bridged triarylamines and -phosphines as materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-9422287-B2 | Bridged triarylamines and -phosphines as materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| WO-2011128017-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011128017-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | TEC, PNMT, TES | ALDH1A1 612/4885POLB 1474/4885KDM4E 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.