SCHEMBL25569838

SCHEMBL25569838

CC(C(=O)c1ccc2c(c1)CCS2)N(C)C(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.32
AAK1 Q2M2I8 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
NPY5R Q15761 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25569841 0.79 SLC6A4 (0.33) SLC6A4POLBGAAMAPT
SCHEMBL25569844 0.78 SLC6A4 (0.31) SLC6A4AAK1
SCHEMBL25569836 0.76 SLC6A4 (0.30) SLC6A4
SCHEMBL27385228 0.75 CA12 (0.41) AAK1MAPTNPY5R
SCHEMBL8645761 0.75 CA12 (0.41) AAK1MAPTNPY5R
SCHEMBL7098217 0.73 ALDH1A1 (0.40) SLC6A4POLBGAAMAPT
SCHEMBL25305808 0.73 ALDH1A1 (0.44)
SCHEMBL25745261 0.73 ALDH1A1 (0.44)
SCHEMBL25745258 0.73 ALDH1A1 (0.44)
SCHEMBL25569848 0.72 CHRNA7 (0.34) AAK1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159487-A1 ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-05-25 US disclosed
US-20230159487-A1 ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT TACTOGEN INC (US) 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159487-A1 ADVANTAGEOUS BENZOTHIOPHENE COMPOSITIONS FOR MENTAL DISORDERS OR ENHANCEMENT SLC6A3, CREBBP, SLC1A2 SLC6A4 21/4885AAK1 1692/4885POLB 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.