Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.36 |
| ▸ | LAP3 | P28838 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129 | 0.82 | ANPEP (0.55) | ANPEPDNPEPRNPEPLAP3RAB9A | |
| SCHEMBL22055144 | 0.75 | KMT2A (0.38) | ANPEPDNPEPCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL22600632 | 0.74 | TSHR (0.40) | ANPEPDNPEPCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL18768475 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL19915434 | 0.74 | DPP7 (0.47) | CYP2C19CYP2D6CYP2C9KMT2A | |
| SCHEMBL20810611 | 0.72 | USP2 (0.46) | ANPEPDNPEPCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL14076746 | 0.72 | ANPEP (0.42) | ANPEPDNPEPLAP3CYP2C19CYP2D6 | |
| SCHEMBL13995614 | 0.71 | CYP2D6 (0.33) | SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL11921172 | 0.70 | KMT2A (0.50) | ANPEPDNPEPCYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24847372 | 0.69 | KMT2A (0.39) | ANPEPDNPEPCYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167105-A1 | BCL-2 PROTEIN INHIBITORS | RECURIUM IP HOLDINGS, LLC | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167105-A1 | BCL-2 PROTEIN INHIBITORS | BCL2, BCL2L1, BCL2L2 | ANPEP 2925/4885DNPEP 2208/4885RNPEP 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.