Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996827 | 0.91 | ACE2 (0.53) | DPP7ACE2RRM1GNAI3GNAO1 | |
| SCHEMBL22600632 | 0.86 | TSHR (0.40) | DPP7CA1CA2USP2CYP2D6 | |
| SCHEMBL20810611 | 0.80 | USP2 (0.46) | DPP7CA1CA2USP2CYP2D6 | |
| SCHEMBL224484 | 0.80 | EPHX1 (0.52) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL25971939 | 0.78 | DPP7 (0.45) | DPP7ACE2KMT2ARRM1GNAI3 | |
| SCHEMBL1753873 | 0.78 | DPP7 (0.60) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL21207627 | 0.76 | GNAI3 (0.47) | DPP7ACE2RRM1GNAI3GNAO1 | |
| SCHEMBL25454649 | 0.76 | EPHX1 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL10248180 | 0.76 | EPHX1 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL14076747 | 0.76 | EPHX1 (0.61) | DPP7RRM1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | REMEGEN CO., LTD. (CN) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | DHFR, FCGR1A, ADCY4 | DPP7 3303/4885ACE2 3841/4885CA1 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.