Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229992 | 0.95 | GPR119 (0.42) | HPGDGPR119ACACBDDB1CRBN | |
| SCHEMBL27162617 | 0.93 | CYP2D6 (0.41) | HPGDGPR119ACACBTPSAB1TPSD1 | |
| SCHEMBL30981206 | 0.89 | ACACB (0.40) | GPR119ACACBNR1H2 | |
| SCHEMBL26925652 | 0.87 | GPR119 (0.45) | HPGDGPR119CYP2D6DDB1CRBN | |
| SCHEMBL27162713 | 0.86 | CYP2D6 (0.38) | HPGDGPR119ACACBALDH1A1CYP2D6 | |
| SCHEMBL24950413 | 0.86 | ACACB (0.39) | HPGDGPR119ACACBDDB1CRBN | |
| SCHEMBL30981400 | 0.85 | CYP11B2 (0.41) | GPR119ACACBNR1H2 | |
| SCHEMBL23249930 | 0.85 | NR1H2 (0.42) | HPGDEPHX1MAPTKDM4ETHRB | |
| SCHEMBL27302369 | 0.83 | GPR119 (0.41) | GPR119ACACBUSP2NR1H2 | |
| SCHEMBL27142937 | 0.81 | GPR119 (0.49) | HPGDGPR119DDB1CRBNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186904-A1 | COMPOUND FOR ANDROGEN RECEPTOR DEGRADATION, AND PHARMACEUTICAL USE THEREOF | Ubix Therapeutics, Inc. (KR) | 2023-05-31 | — | — | EP | disclosed |