⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27282036 | 0.89 | SMPD1 (0.35) | — | |
| SCHEMBL25572013 | 0.87 | — | — | |
| SCHEMBL20465720 | 0.87 | — | — | |
| SCHEMBL25485086 | 0.85 | — | — | |
| SCHEMBL13882144 | 0.82 | FBP1 (0.31) | — | |
| SCHEMBL25572011 | 0.80 | — | — | |
| SCHEMBL13882141 | 0.79 | FBP1 (0.33) | — | |
| SCHEMBL19078924 | 0.79 | — | — | |
| SCHEMBL19051013 | 0.79 | — | — | |
| SCHEMBL19760424 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238435-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240209119-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING DYSTROPHINOPATHIES | DYNE THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240066140-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240016952-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-11839660-B2 | Anti-transferrin receptor antibody and uses thereof | DYNE THERAPEUTICS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-20230346967-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING DYSTROPHINOPATHIES | DYNE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230346966-A1 | MUSCLE-TARGETING COMPLEXES AND USES THEREOF IN TREATING MUSCLE ATROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230330562-A1 | METHODS OF PREPARING PROTEIN-OLIGONUCLEOTIDE COMPLEXES | DYNE THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230330247-A1 | MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230321264-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-20230285582-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230285586-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING DYSTROPHINOPATHIES | DYNE THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230256113-A1 | ANTI-TRANSFERRIN RECEPTOR ANTIBODY AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230226212-A1 | MUSCLE-TARGETING COMPLEXES AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230203180-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR MODULATION OF GENES ASSOCIATED WITH MUSCLE HEALTH | DYNE THERAPEUTICS, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-11679161-B2 | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy | DYNE THERAPEUTICS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-11672872-B2 | Anti-transferrin receptor antibody and uses thereof | DYNE THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11648318-B2 | Anti-transferrin receptor (TFR) antibody and uses thereof | DYNE THERAPEUTICS, INC. (US) | 2023-05-16 | — | — | US | disclosed |
| US-20230144436-A1 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11638761-B2 | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy | DYNE THERAPEUTICS, INC. (US) | 2023-05-02 | — | — | US | disclosed |