⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19703599 | 0.84 | — | — | |
| SCHEMBL19274375 | 0.74 | BACE1 (0.32) | — | |
| SCHEMBL9311554 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL9311557 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL27256070 | 0.69 | — | — | |
| SCHEMBL18909500 | 0.68 | — | — | |
| SCHEMBL20953377 | 0.67 | BACE1 (0.33) | — | |
| SCHEMBL18944218 | 0.67 | CES2 (0.32) | — | |
| SCHEMBL20403953 | 0.66 | CYP3A4 (0.31) | — | |
| SCHEMBL19059485 | 0.65 | GRIK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174605-A1 | IL-2 SEQUENCES AND USES THEREOF | Ascendis Pharma Oncology Division A/S (DK) | 2023-06-08 | — | — | US | disclosed |