SCHEMBL25575142

SCHEMBL25575142

CC(=O)[C@H]1CCCC[C@@H]1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PEPD P12955 1/20 0.45
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
GRM4 Q14833 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16141882 1.00 KDM4E (0.47) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL1115372 1.00 KDM4E (0.47) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL26839145 1.00 KDM4E (0.47) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL18435274 1.00 KDM4E (0.47) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL11400422 0.97 KDM4E (0.46) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL28885167 0.97 KDM4E (0.46) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL7755799 0.95 PEPD (0.50) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL25575137 0.95 PEPD (0.50) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL26181646 0.95 PEPD (0.50) KDM4EHTTSMN1; SMN2PEPDALDH1A1
SCHEMBL25575140 0.95 PEPD (0.50) KDM4EHTTSMN1; SMN2PEPDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20230287365-A1 COMPOSITIONS AND METHODS FOR DECREASING INFLAMMATION BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2023-09-14 US disclosed
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A KDM4E 4753/4885HTT 4145/4885SMN1; SMN2 4221/4885
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A KDM4E 4734/4885HTT 4471/4885SMN1; SMN2 4596/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A KDM4E 4753/4885HTT 4145/4885SMN1; SMN2 4221/4885
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A KDM4E 4734/4885HTT 4471/4885SMN1; SMN2 4596/4885
US-20230287365-A1 COMPOSITIONS AND METHODS FOR DECREASING INFLAMMATION ENTPD1, ENTPD2, ENTPD5 KDM4E 3787/4885HTT 4651/4885SMN1; SMN2 3888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.