SCHEMBL2557724

SCHEMBL2557724

C=CCNC(=O)COc1c(C=O)cccc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
KDM4E B2RXH2 4/20 0.47
POLB P06746 2/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 2/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
HSD17B10 Q99714 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
NFE2L2 Q16236 1/20 0.44
NPC1 O15118 3/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
TLR2 O60603 1/20 0.43
ERN1 O75460 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2559925 0.89 ALDH1A1 (0.48) KDM4EPOLBRAB9ASMN1; SMN2HTT
SCHEMBL29952197 0.86 ALDH1A1 (0.56) SRCKDM4EPOLBRAB9ASMN1; SMN2
SCHEMBL2556798 0.84 HSD17B10 (0.53) SRCKDM4EPOLBRAB9ASMN1; SMN2
SCHEMBL2555240 0.83 SRC (0.56) SRCKDM4EPOLBRAB9ASMN1; SMN2
SCHEMBL20150988 0.83 SRC (0.56) SRCKDM4EPOLBRAB9AHSD17B10
SCHEMBL15330855 0.83 HPGD (0.55) SRCPOLBRAB9AHSD17B10NPSR1
SCHEMBL29954842 0.83 KMT2A (0.59) SRCRAB9ASMN1; SMN2GLAGAA
SCHEMBL2554954 0.83 SRC (0.50) SRCPOLBRAB9ASMN1; SMN2HTT
SCHEMBL2556757 0.83 SRC (0.50) SRCKDM4EPOLBRAB9AGAA
SCHEMBL29952098 0.83 SRC (0.50) SRCKDM4EPOLBRAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
EP-2558577-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2013-02-20 EP disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed