Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335743 | 0.79 | MAPT (0.47) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL5408760 | 0.76 | POLB (0.55) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL4879569 | 0.72 | PTGS1 (0.48) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL10561726 | 0.71 | CA12 (0.58) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL19240298 | 0.71 | SMN1; SMN2 (0.56) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL15560058 | 0.69 | PTGS1 (0.61) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL15559375 | 0.69 | ACHE (0.51) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL15558972 | 0.69 | MAPT (0.46) | MAPTKMT2AMEN1POLBTDP1 | |
| SCHEMBL6448561 | 0.69 | SCN2A (0.50) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28766878 | 0.68 | HTT (0.46) | MAPTKMT2AMEN1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |