Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543835 | 0.81 | MAPT (0.56) | POLBMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8335743 | 0.79 | MAPT (0.47) | POLBXDHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4879569 | 0.76 | PTGS1 (0.48) | POLBXDHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2557804 | 0.76 | MAPT (0.44) | POLBXDHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10561726 | 0.75 | CA12 (0.58) | POLBXDHMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19240298 | 0.74 | SMN1; SMN2 (0.56) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6250200 | 0.72 | POLB (0.55) | POLBALDH1A1SMN1; SMN2NFKB1KDM4E | |
| SCHEMBL11328079 | 0.72 | MAPT (0.72) | POLBMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15560058 | 0.72 | PTGS1 (0.61) | POLBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL15558972 | 0.72 | MAPT (0.46) | POLBMAPTALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7195649-B2 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | WELLA AG (DE) | 2007-03-27 | — | — | US | disclosed |
| EP-1562540-B1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| EP-1562540-A1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-04-21 | — | — | US | disclosed |
| WO-2004047781-A1 | N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | WO | disclosed |
| US-4994209-A | Optically transparent solid solution of organic compound in polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0017768-A1 | Reactive dyestuffs and their use | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050081312-A1 | N-aryl-4,5-diaminopyrazoles and dyes containing said compounds | KRT18, F12, HCN3 | POLB 1807/4885XDH 746/4885MAPT 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.