SCHEMBL2558596

SCHEMBL2558596

CC(C)(C)OC(=O)CNC(=O)CN

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.41
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
PTPRC P08575 2/20 0.37
GAA P10253 2/20 0.36
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
DGAT1 O75907 1/20 0.34
CYP2D6 P10635 1/20 0.34
TET2 Q6N021 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TERT O14746 1/20 0.33
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL715683 0.98 RECQL (0.39) RECQLMAOAMAOBPTPRCGAA
SCHEMBL13292141 0.96 RECQL (0.38) RECQLMAOAMAOBPTPRCGAA
SCHEMBL6575441 0.96 RECQL (0.38) RECQLMAOAMAOBPTPRCGAA
Hydrochloric Acid SCHEMBL9087860 0.94 RECQL (0.37) RECQLMAOAMAOBPTPRCGAA
SCHEMBL27601805 0.87 RECQL (0.33) RECQLMAOAMAOBPTPRCHRH3
SCHEMBL29004075 0.85 RECQL (0.36) RECQLMAOAMAOBGAACA12
SCHEMBL1119918 0.84 RECQL (0.37) RECQLMAOAMAOBGAACA12
SCHEMBL7376338 0.83 RECQL (0.41) RECQLMAOAMAOBPTPRCGAA
SCHEMBL29706242 0.82 MAOA (0.35) RECQLMAOAMAOBGAACA12
Hydrochloric Acid SCHEMBL7991659 0.81 MLYCD (0.39) RECQLMAOAMAOBGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676483-A1 IMPROVED LINKER-PAYLOADS FOR ANTIBODY CONJUGATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS THEREOF OBI Pharma, Inc. (TW) 2026-01-14 EP disclosed
EP-4637748-A2 PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF Merck Sharp & Dohme LLC (US) 2025-10-29 EP disclosed
EP-4608453-A1 EXATECAN-DERIVED ADC LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF Merck Sharp & Dohme LLC (US) 2025-09-03 EP disclosed
EP-4558511-A2 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF Firefly Bio, Inc. (US) 2025-05-28 EP disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
EP-4541796-A1 EXATECAN DERIVATIVES AND USE THEREOF Hangzhou Adcoris Biopharma Co., Ltd (CN) 2025-04-23 EP disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
WO-2025064733-A1 IMPROVED LINKER-PAYLOADS FOR ANTIBODY CONJUGATION, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS THEREOF OBI PHARMA, INC. (TW) 2025-03-27 WO disclosed
EP-4489792-A1 PHENYL MALEIMIDE LINKER AGENTS Firefly Bio, Inc. (US) 2025-01-15 EP disclosed
CN-118434765-A BCMA monoclonal antibodies and antibody-drug conjugates 杭州多禧生物科技有限公司 2024-08-02 CN disclosed
WO-2011130613-A1 TARGETED PYRROLOBENZODIAZAPINE CONJUGATES SEATTLE GENETICS, INC. (US) 2011-10-20 WO disclosed
CN-1886114-B Parakeratosis inhibitor and composition for external use on skin SHISEIDO CO LTD 2011-08-10 CN disclosed
CN-100482285-C Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ED-B PHILOGEN S P A SCHERING AG (IT) 2009-04-29 CN disclosed
CN-1886114-A Parakeratosis inhibitor and composition for external use on skin SHISEIDO CO LTD (JP) 2006-12-27 CN disclosed
CN-1849144-A Targeting of tumor vasculature using radiolabelled antibody l19 against fibronectin ED-B PHILOGEN SPA (IT) 2006-10-18 CN disclosed
EP-0649414-B1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES ARDENT PHARMACEUTICALS INC (US) 2003-04-16 EP disclosed
US-5854249-A Opioid diarylmethylpiperazines and piperidines DELTA PHARMACEUTICALS, INC. (US) 1998-12-29 US disclosed
US-5658908-A RECEPTOR BINDING SPECIES FOR MEDIATING ANALGESIA, COMBATTING DRUG ADDICTION, DRUG OVERDOSE DELTA PHARMACEUTICALS, INC. (US) 1997-08-19 US disclosed
EP-0649414-A1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES THE WELLCOME FOUNDATION LIMITED (GB) 1995-04-26 EP disclosed
WO-1993015062-A1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES THE WELLCOME FOUNDATION LIMITED (GB) 1993-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS RECQL 849/4885MAOA 4755/4885MAOB 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.