⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815562 | 0.76 | — | — | |
| SCHEMBL873878 | 0.70 | CA1 (0.30) | — | |
| SCHEMBL23173366 | 0.69 | — | — | |
| SCHEMBL636022 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL777753 | 0.65 | NPSR1 (0.37) | — | |
| SCHEMBL18717712 | 0.63 | — | — | |
| SCHEMBL780031 | 0.63 | NPSR1 (0.36) | — | |
| SCHEMBL15496978 | 0.62 | — | — | |
| SCHEMBL883061 | 0.61 | — | — | |
| SCHEMBL6735817 | 0.60 | NPSR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667613-B2 | Antiviral pyrazolopyridinone compounds | NOVARTIS AG (CH) | 2023-06-06 | — | — | US | disclosed |