Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15646561 | 0.80 | ERN1 (0.48) | PTPRCPTPN1ERN1PIK3R1PIK3CA | |
| SCHEMBL5781695 | 0.77 | IMPDH2 (0.48) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL26259973 | 0.75 | IMPDH2 (0.55) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL26259960 | 0.75 | IMPDH2 (0.60) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL28749556 | 0.74 | ALDH1A1 (0.54) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL10035259 | 0.74 | CYP2A6 (0.54) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL5648236 | 0.74 | ALDH1A1 (0.54) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL395258 | 0.74 | ALDH1A1 (0.54) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL28051267 | 0.74 | IMPDH2 (0.47) | IMPDH2ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL12856701 | 0.73 | PTPRC (0.56) | PTPRCPTPN1ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |