Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535693 | 0.84 | L3MBTL1 (0.47) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL121347 | 0.83 | NPSR1 (0.41) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL18995149 | 0.81 | NPSR1 (0.39) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL2718634 | 0.81 | NPSR1 (0.39) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL11912371 | 0.80 | NPSR1 (0.45) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL536166 | 0.80 | KDM4E (0.50) | NPSR1L3MBTL1 | |
| SCHEMBL29572369 | 0.79 | CYP4A11 (0.44) | NPSR1MAPK8MAPK9MAPK10 | |
| SCHEMBL28615076 | 0.78 | — | — | |
| SCHEMBL29598445 | 0.76 | NPSR1 (0.35) | NPSR1L3MBTL1MAPK8MAPK9MAPK10 | |
| SCHEMBL28706141 | 0.76 | MAPT (0.49) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012030907-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-08 | — | — | WO | disclosed |