Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995149 | 0.85 | NPSR1 (0.39) | NPSR1L3MBTL1 | |
| SCHEMBL29572369 | 0.83 | CYP4A11 (0.44) | NPSR1 | |
| SCHEMBL535693 | 0.81 | L3MBTL1 (0.47) | KMT2ANPSR1L3MBTL1 | |
| SCHEMBL121347 | 0.80 | NPSR1 (0.41) | NPSR1L3MBTL1 | |
| SCHEMBL255890 | 0.80 | NPSR1 (0.41) | NPSR1L3MBTL1 | |
| SCHEMBL4159802 | 0.79 | MMP2 (0.49) | LMNACYP1A2L3MBTL1 | |
| SCHEMBL2718634 | 0.79 | NPSR1 (0.39) | KDM4EMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL29598453 | 0.77 | KDM4E (0.42) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL17398618 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL23538248 | 0.75 | NPSR1 (0.46) | KDM4EALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414352-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117704-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-14 | — | — | WO | disclosed |