Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.53 |
| ▸ | EIF4E | P06730 | 1/20 | 0.53 |
| ▸ | TTK | P33981 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22431103 | 0.88 | TTK (0.54) | MKNK1MKNK2TTKALDH1A1CYP3A4 | |
| SCHEMBL15651199 | 0.80 | LRRK2 (0.55) | MKNK1MKNK2EIF4ETTKJAK2 | |
| SCHEMBL12492042 | 0.78 | ALDH1A1 (0.62) | MKNK1MKNK2TTKALDH1A1CYP3A4 | |
| SCHEMBL30880505 | 0.76 | KIT (0.49) | MKNK1MKNK2EIF4ETTKJAK2 | |
| SCHEMBL25589670 | 0.74 | TTK (0.59) | TTK | |
| SCHEMBL17024291 | 0.72 | ALDH1A1 (0.57) | TTKALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL26598724 | 0.72 | LRRK2 (0.46) | MKNK1MKNK2EIF4ETTKJAK2 | |
| SCHEMBL29399235 | 0.71 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL48945 | 0.71 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL28862512 | 0.70 | KIT (0.48) | MKNK1MKNK2EIF4EJAK2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | VORONOIBIO INC. (KR) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183243-A1 | HETEROARYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | TTK, TTBK1, TTBK2 | MKNK1 146/4885MKNK2 162/4885EIF4E 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.