Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880622 | 0.88 | LOXL2 (0.53) | LOXL2MAP4K3FGFR1FGFR2FGFR3 | |
| SCHEMBL25589668 | 0.76 | MKNK1 (0.53) | KITLRRK2JAK2EIF4EMKNK1 | |
| SCHEMBL15651199 | 0.71 | LRRK2 (0.55) | KITLRRK2JAK2EIF4EMKNK1 | |
| SCHEMBL2574462 | 0.70 | KIT (0.48) | KITLRRK2JAK2EIF4EMKNK1 | |
| SCHEMBL30839799 | 0.70 | ALDH1A1 (0.50) | KITABL1 | |
| SCHEMBL27185954 | 0.70 | ALDH1A1 (0.50) | KITABL1 | |
| SCHEMBL30880679 | 0.68 | IKBKE (0.44) | LOXL2JAK2FGFR1FGFR2FGFR3 | |
| SCHEMBL30880662 | 0.68 | KIT (0.47) | KITLOXL2FGFR1FGFR2FGFR3 | |
| SCHEMBL26598724 | 0.68 | LRRK2 (0.46) | KITLRRK2JAK2EIF4EMKNK1 | |
| SCHEMBL30880509 | 0.67 | FGFR1 (0.49) | KITLOXL2LRRK2MKNK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078513-A1 | CONDENSED AZINES FOR TREATING CANCER | CHENGDU ANTICANCER BIOSCIENCE , LTD. (CN) | 2024-04-18 | — | — | WO | disclosed |