Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25590669 | 0.88 | TP53 (0.44) | MAPTKMT2AALDH1A1MEN1TP53 | |
| SCHEMBL25590677 | 0.86 | ATR (0.40) | ATRADORA3MAPTKMT2AALDH1A1 | |
| SCHEMBL25590487 | 0.83 | LRRK2 (0.46) | ATRADORA3MAPTKMT2AALDH1A1 | |
| SCHEMBL25590495 | 0.77 | RAB9A (0.55) | ATRMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL25590474 | 0.73 | ATR (0.51) | ATRADORA3MAPTKMT2AALDH1A1 | |
| SCHEMBL25590490 | 0.73 | ATR (0.58) | ATRMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL25593585 | 0.73 | ATR (0.43) | ATRMAPTKMT2ATHRBPTGER4 | |
| SCHEMBL25593240 | 0.72 | FLT3 (0.49) | ATRADORA3MAPTALDH1A1TP53 | |
| SCHEMBL25593788 | 0.71 | ATR (0.48) | ATRKMT2AALDH1A1MEN1TP53 | |
| SCHEMBL25590895 | 0.70 | CLK2 (0.44) | ATRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |