Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | QPCT | Q16769 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25591687 | 0.89 | MAPT (0.62) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL25590486 | 0.88 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2QPCTKMT2A | |
| SCHEMBL25593240 | 0.80 | FLT3 (0.49) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL25590490 | 0.78 | ATR (0.58) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL25590489 | 0.77 | ATR (0.45) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL25590677 | 0.77 | ATR (0.40) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL12082836 | 0.75 | RAB9A (0.73) | RAB9ANPC1SMN1; SMN2QPCTKMT2A | |
| SCHEMBL30050799 | 0.75 | QPCT (0.75) | RAB9ANPC1SMN1; SMN2QPCTKMT2A | |
| SCHEMBL25593788 | 0.74 | ATR (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25590474 | 0.74 | ATR (0.51) | RAB9ANPC1SMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088435-A1 | PREPARATION FOR TRISUBSTITUTED PYRIDINE DERIVATIVE AND APPLICATION AS AROMATIC HYDROCARBON RECEPTOR MODULATOR | 成都奥睿药业有限公司 | 2023-05-25 | — | — | WO | disclosed |